Mouth Corner Botox Review I received Botox on the depressors of both mouth corners and now the corners of my mouth are rising naturally. When you smile, your mouth naturally goes up, and even if you intentionally force your mouth down, it doesn't go down easily. This was my first time receiving Botox treatment on the corners of my mouth. I was treated with domestic Botox and the price was in the 90,000-100,000 won range. It took about 2 weeks and there was no discomfort. Satisfaction rating is 5 stars.