Side effects of Botox treatment ※Square jaw The skin around the lower jaw at the front of the mouth where Botox was applied protrudes , the front chin becomes U-shaped , cheek depressions appear ※After receiving Botox under the eyes, the mid-face area becomes saggy, sagging front cheeks, Indian wrinkles, and nasolabial folds become worse. If you get Botox, it will last for several months. I took it lightly because I thought it would come back later, but I guess Totox is not for me. I've been suffering from side effects for a year.