This is a late review. In September, I had Rejuran Healer 2cc + Rejuran Eye hand injection and it was more effective on fine wrinkles under the eyes rather than improving skin defects. The procedure itself was so painful that I shed tears. I'm the type to put up with it, so I said I only use anesthetic cream . They say that Chanel injections are effective, and Rejuran is like a fundamental nutritional supplement . I heard that the foundation was clumping in the wrinkles under the eyes, but after a month of receiving Rejuran, it was nice that those symptoms disappeared . Hope this helps...