If you take Botox for the chin, temples, and temporal muscles over a period of time, it will definitely be effective. I have been taking it consistently for 6 years already. I started using domestic Innotox, then Nabota for a while, and then Coretox. I feel like it lasts longer, as long as I don't apply too much! I used to suffer from headaches, but the headaches seem to have eased.