The effect was a subtle difference for me personally, but nevertheless, the time when the effect would dissipate = (for me) I feel like my nose is getting bigger every one year. It seems like it's because I've gained weight every winter, and I'm worried about my nose like a ghost. So, I had re-treatment 3 times in a year cycle, and it was less annoying after I did it . The director is good, but I have seen bad reviews a few times, so I want to do something. Calm and quiet. kind